Wham clusters all of the candidate breakpoints and rounds their positions to the nearest tenth foundation pair. The place with the highest go through aid is described. If the tender-clipped consensus sequence may be aligned into the putative breakpoint region using the Smith-Waterman algorithm, the breakpoint is more refined to The situation on the

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The soft-clipped sequences that overhang the breakpoint are collapsed right into a consensus sequence employing a numerous sequence alignment (MSA) presented within the seqAn library [27]. Wham applies 3 filters towards the consensus sequences. Breakpoints are not documented in situations wherever consensus sequences are shorter than 10 bp or incor